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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Biomaterials. 2011 Jun 17;32(28):6823–6831. doi: 10.1016/j.biomaterials.2011.05.061

Table 1.

Experimental conditions for the nine treatment sites

Group Insertion depth (μm) Flow rate (mL/min)
T1 500 0.3
T2 750 0.3
T3 1000 0.3
T4 4000 0.3
T5 intradermal1 0.3
T6 1000 / 500 2 0.3
T7 750 1.0
T8 750 0.1
T9 750 0.3 (hyaluronidase)3
1

A 26-gauge, intradermal-bevel hypodermic needle was used to inject intradermally using the Mantoux technique.

2

A microneedle was inserted to a depth of 1000 μm and then retracted to a depth of 500 μm before injection.

3

A solution of hyaluronidase was injected, instead of saline.