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Microglia from p53−/− mice express markers of alternative activation. Real-Time quantitative RT-PCR (Q-PCR) results on microglia from p53+/+ and p53−/− mice are shown for two genes upregulated following alternative activation of macrophages, Ym1 and FIZZ1 (n=3 from separate culture experiments and Q-PCR runs, p<0.001 by t-test).
