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Secondary structures of RPRs from Bacteria (e.g., Escherichia coli) and Archaea [e.g., Pyrococcus furiosus (Pfu; type A) and Methanocaldococcus jannaschii (Mja; type M)].27,75 The universally conserved bulged uridine in the P4 helix of all RPRs is enclosed in a colored circle. A deletion (ΔU) mutation made at this position in the Mja RPR is also indicated.
