Figure 4.
(a) Phosphorylated p70S6k and total p70S6k in the Agtr2–/Y and wild-type mouse hearts. Lane 1: aortic-banded Agtr2–/Y; lane 2: aortic-banded wild-type; lane 3: sham-operated Agtr2–/Y; lane 4: sham-operated wild-type. AP < 0.05. Data are representative of three independent experiments with nearly identical results. (b) Nkx 2.5, GATA4, MEF2C, β-MHC, ANP, and GAPDH in aortic-banded Agtr2–/Y and wild-type mouse hearts. Lane 1: Agtr2–/Y before surgery; lane 2: wild-type before surgery; lane 3: Agtr2–/Y 2 days after surgery; lane 4: Agtr2–/Y 2 weeks after surgery; lane 5: wild-type 2 days after surgery; lane 6: wild-type 2 weeks after surgery. Data are representative of three independent experiments with nearly identical results.