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. Author manuscript; available in PMC: 2012 Jul 27.
Published in final edited form as: Brain Res. 2011 Jun 2;1403:45–56. doi: 10.1016/j.brainres.2011.05.058

Figure 1.

Figure 1

Combining AdGDNF and L-arginine Significantly Reduces Contusion Size. A) Coronal section of an animal that received a CCI, but received no treatment post injury. B) Animal received a CCI and was treated with AdGDNF and L-arginine immediately post-injury resulting in a significantly smaller contusion. CCI=Contusion cavity; CC = Corpus Callosum; ST=Striatum; LV= Lateral Ventricle; Scale bar (A&B) = 250μm C) Volume of Remaining Cortex - Animals treated with AdGDNF and L-arginine post-CCI had significantly smaller contusions (greater amount of remaining cortex) than animals in the CCI group, which did not receive any treatment; as well as injured animals treated with AdGDNF or L-arginine alone (*p<0.05 significantly different from sham; †significantly different from CCI, CCI+L-arg, CCI+AdGDNF p<0.05)