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. 2010 Nov 16;68(2):497–504. doi: 10.1007/s00280-010-1503-x

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© The Author(s) 2010

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Fig. 3 — Therapeutic effect of S-1 on the progression of Y-MESO-14 tumor in SCID mice. Y-MESO-14 cells developed thoracic tumors (upper left, black arrows) and pleural effusion (lower left, white arrows) in mice treated with vehicle. Treatment with S-1 significantly decreased the mass of tumors (upper right) and bloody pleural effusion (lower right)