Table 3.
Results of Linear Regression Models of Body Composition Measures (Year 1) as Independent Variables and FEV1 (mL) (Year 1) as the Dependent Variable
| N = 1893 | Model 1 | Model 2 | Model 3 | |||
| Beta (SE) | p Value | Beta (SE) | p Value | Beta (SE) | p Value | |
| Total hip bone mineral density (gm/cm2) | 1246.12 (83.60) | <.001 | 210.75 (78.44) | .007 | — | — |
| Fat mass (kg) | −9.29 (1.72) | <.001 | −2.12 (1.34) | .113 | — | — |
| Subcutaneous adipose tissue (cm2) | −1.50 (0.13) | <.001 | −0.05 (0.11) | .669 | — | — |
| Visceral adipose tissue (cm2) | 0.73 (0.23) | .001 | −1.14 (0.17) | <.001 | −1.66 (0.18) | <.001 |
| Total thigh muscle area (cm2) | 5.37 (0.23) | <.001 | 1.43 (0.31) | <.001 | 1.87 (0.35) | <.001 |
| Total thigh intermuscular fat area (cm2) | −3.58 (1.23) | .004 | −2.17 (0.92) | .018 | — | — |
| Height (cm) | 43.05 (1.24) | <.001 | 29.00 (1.68) | <.001 | 27.77 (1.75) | <.001 |
Notes: Model 1: Body composition measures were entered in separate unadjusted models. Model 2: Model 1 + clinic site, age, sex, race, FEV1 or FVC quality score, and height (CT and DEXA measures only). Model 3: Model 2 + remaining body composition measures, smoking, prevalent cardiovascular disease, osteoporosis, emphysema, and chronic bronchitis. Y1 FEV1 (N = 88) or Y1 FVC (N = 196) of quality score <2 excluded. Model 3 results provided for variables retained in forward selection procedure (p-entry = .20).