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. 2011 Jun 15;203(12):1753–1762. doi: 10.1093/infdis/jir186

Table 1.

Pathway Analysis Statistics

Pathway Group enrichment P valuea # of predicted targets in pathway for mock miRNA controls
# of predicted targets in pathway for miRNAs in Table 2b
Mean controlb Maximum controlb
ECM-receptor interaction 0.0046 22 36 45
Focal adhesion 0.017 66 93 101
Small cell lung cancer 0.039 24 33 39

NOTE. aThe group enrichment P value represents the enrichment of predicted targets for a pathway relative to mock-predicted targets.

bTwenty control miRNA sets were generated that had the same characteristics as the test miRNA family. The mean and maximum number of miRNAs in simulations from these control sets that are predicted to target the pathway are indicated, which can be compared with the actual number of observed miRNAs predicted to target the pathway. See Supplementary Data for more details.