TABLE V.
Predictors of Breathing Zone Mouse Allergen Concentrations Among Mouse Handlers
Predictors of Exposure | Avg. Mus m 1 (ng/m3) Median (IQR)A | p-value | Peak Mus m 1 (ng/m3) Median (IQR)A | p-value | |
---|---|---|---|---|---|
Mouse handler | Yes (n = 97) | 4.14 (0.70–12.12) | <0.001 | 6.70(1.27–18.45) | <0.001 |
No (n = 71) | 0.21 (BDB –0.63) | 0.31 (BDB –1.17) | |||
Primary task | Animal care (n = 42) | 8.73 (3.56–18.68) | <0.001 | 11.44 (4.67–24.08) | <0.001 |
Husbandry (n = 26) | 5.83 (3.26–14.95) | 7.82 (3.46–18.75) | |||
Laboratory exp. (n = 25) | 0.36 (0.07–1.77) | 0.61 (0.14–1.81) | |||
Type of mice | Live, conscious (n = 92) | 4. 46 (0.74–13.53) | 6.79 (1.29–18.60) | 0.89 | |
Dead mice (n = 3) | |||||
4.11 (BDB –379.86) | 0.99 | 8.08 (BDB –682.50) | |||
Frequency of mouse handling | <1 day/week (n = 4) | 0.20 (BDB –2.26) | <0.001 | 0.31 (BDB –4.34) | <0.001 |
1–2 days/week (n = 13) | 0.38 (0.06–1.93) | 0.65 (0.13–3.43) | |||
3–4 days/week (n = 16) | 0.84 (0.18–2.41) | 1.07 (0.27–2.80) | |||
5+ days/week (n = 63) | 7.73 (3.49–18.54) | 11.32 (4.57–23.44) |
Note: Peak concentration was defined as the highest concentration of Day 1 and Day 2 measurements.
Interquartile range.
BD, below detection. The limit of detection for the breathing zone Mus m 1 concentration ranged from 0.05–0.18 ng/m3.