TABLE 2.

Summary of Mutations in the gpt Gene of Male and Female B6C3F1 Neonates 21 Days After Treatment with Multiple Doses (3 × 2 mg/kg) of AFB₁

Mutation types	Control		AFB1
	Male	Female	Male	Female
Transition
G:C to A:T	9 (38)	3 (60)	8 (17)	13 (17)
A:T to G:C	1 (4)	0 (0)	0 (0)	1 (1)
Transversion
G:C to T:A	4 (17)	1 (20)	31 (66)	45 (58)
G:C to C:G	1 (4)	0 (0)	1 (2)	13 (17)
A:T to T:A	1 (4)	0 (0)	0 (0)	2 (3)
A:T to C:G	0 (0)	0 (0)	1 (2)	0 (0)
Deletion (bp)
1	4 (17)	0 (0)	6 (13)	2 (3)
>1	0 (0)	0 (0)	0 (0)	0 (0)
Insertion	4 (17)	1 (20)	0 (0)	1(1)
Total number of mutants	24 (100)	5 (100)	47 (100)	77 (100)

Note. Percentage of each type of mutation is given in parentheses.