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Effect of incubation of pancreas fragments with quercetin (50 μM) on trypsinogen activation. Trypsin activity in the homogenates was measured according to the method described in the text. Values are mean ± SEM obtained from at least three separate experiments. AP < 0.05 when cerulein-treated freshly prepared fragment values are compared with basal values. BP < 0.05 when quercetin-incubated cerulein-stimulated fragments are compared with cerulein-stimulated 12-hour control fragments.
