TABLE 1.

Known mercuric conjugates that are substrates for OAT1

MDCK, Madin-Darby canine kidney; h, human; r, rat; NAC, N-acetylcysteine.

Substrate	Assay	Transporter	Km	Ref.
			μm
Cys-S-Hg-S-Cys	MDCK II	hOAT1	91	11
Hcy-S-Hg-S-Hcy	MDCK II	hOAT1	128	11
Hg2+ (NAC-S-Hg-S-NAC)	MDCK II	hOAT1	144	10
MeHg-2,3-dimercapto-1-propanesulfonic acid	X. laevis	rOAT1	9	31
MeHg-N-acetyl-l-cysteine	X. laevis	rOAT1	31	31
N-Acetyl-l-cysteine-Hg2+	MDCK II	hOAT1	44	12