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Prenatal skeletal changes in Osx::CXCR4fl/fl mice. A, representative images of newborn (day 1) Osx::CXCR4fl/fl mice (KO) and Cre-null littermates used as WT controls (upper panel) and Alcian blue/Alizarin red staining of E18.5 embryos (lower panel). B, Alcian blue/Alizarin red staining of entire heads (upper panel) and amplified regions of calvaria (framed areas) and nose (indicated by arrows) of E18.5 embryos (lower panels). WT and KO from two different litters were observed.
