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. 2011 Jul 21;2:37. doi: 10.3389/fphys.2011.00037

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Copyright © 2011 Behr, Longaker and Quarto.

This is an open-access article subject to a non-exclusive license between the authors and Frontiers Media SA, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and other Frontiers conditions are complied with.

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Activation of canonical Wnt-signaling in embryonic and postnatal cranial sutures. (A) Xgal staining of LAM suture harvested from Wnt1Cre/R26R mouse. Xgal staining indicates the neural-crest origin of the LAM suture mesenchyme. The boxed area is enlarged to the right. (B) Xgal staining of PF, COR SAG, and LAM suture mesenchymes in Axin2^+/− mice from e18.5 to p180. Scale bar: 100 μm. Inserts represent zoomed areas of the coronal sutures. Dashed lines indicate the bone plates. (C) Quantification of Xgal staining of different cranial suture mesenchymes in Axin2^+/− mice at day p25 and p180.