Table 1.
Binding affinity for Hsp90 from SKBr3 cellular extracts.
| Compound | IC50 (nM) |
|---|---|
| GM | 15.4 |
| PU-H71 | 22.4 |
| 5 | 19.8 |
| 7 | 67.1 |
| NVP-AUY922 | 4.1 |
| 10 | 7.0 |
| SNX-2112 | 15.1 |
| 18 | 210.1 |
| 20 | 24.7 |
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