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. 2011 Jul 15;25(14):1510–1527. doi: 10.1101/gad.2051011

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Copyright © 2011 by Cold Spring Harbor Laboratory Press

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Figure 5. — Global changes in gene expression profile of mammary tumors from CKO-MT mice. (A,B) Heat map of genes showing differential up-regulation (A) or down-regulation (B) of at least twofold in tumors from CKO-MT mice compared with those from Crtl-MT mice. Representative up-regulated and down-regulated genes are marked on the right. (C,D) A select group of up-regulated genes were validated using qRT–PCR. The mean ± SD (n = 3) of relative levels (normalized to Ctrl-MT tumors) from three independent experiments is shown.