Table 1.

C57BL/6 mice showed significantly heightened BAL protein levels and inflammatory changes in the BAL phospholipid profile in comparison with Balb/c mice following allergic sensitization and challenge with Af.

MOUSE STRAIN		Protein, μg per lung		Phospholipid, μg per lung
		LA	SA	LA	SA
BALB/C	Naive	94 ± 19	1,075 ± 154	144 ± 25	78 ± 11
	Sensitized	99 ± 14	1,059 ± 108	146 ± 12	106 ± 14
C57BL/6	Naive	56 ± 6	1,283 ± 200	148 ± 22	97 ± 6
	Sensitized	56 ± 7	1,998 ± 266*#	100 ± 12*	146 ± 24*

Protein and phospholipid content were analyzed from the large aggregate (LA) and the small aggregate (SA) surfactant fractions of naïve and sensitized mice as described. Data are expressed as amount of protein or phospholipid (micrograms) per mouse lung. Mean ± SEM of n = 16–22 mice per group were calculated after deriving the average of the results from two independent experiments. *p < 0.05 Sensitized vs Naive; #p < 0.05 C57BL/6 vs Balb/c.