Table.
Echocardiographic measurements in NTG and TRE-PGC-1βMHCrtTA mice at baseline and with LPS
| NTG (PBS) | NTG (LPS) | PGC-1β (PBS) | PGC-1β (LPS) | |
|---|---|---|---|---|
| HR, beats/min | 393±17 | 463±11* | 385±23 | 468±9* |
| LVEDD (mm) | 3.57±0.14 | 3.65±0.09 | 3.65±0.09 | 3.52±0.06 |
| LVESD (mm) | 1.69±0.06 | 2.78±0.10* | 1.80±0.07 | 2.19±0.06*‡ |
| FS (%) | 52.5±0.6 | 24.0±1.4* | 50.8±1.2 | 37.9±0.9*‡ |
| LPWT (mm) | 0.91±0.03 | 0.96±0.02 | 0.94±0.03 | 0.94±0.03 |
NTG (non-transgenic); HR (heart rate); LVEDD (left ventricular end-diastolic diameter); LVESD (left ventricular end-systolic diameter); FS (fractional shortening); LPWT (left ventricular posterior wall thickness); PGC-1β (TRE-PGC-1βMHCrtTA mice);
*
p <0.05 PBS vs. LPS,
‡
p <0.05 NTG vs. PGC-1β via two-way ANOVA analysis.