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Family 1 pedigree and haplotypes; proband’s (III:1) oral photos and radiograph. (A) Pedigree of family 1. The haplotype of each individual is shown below the symbol. Red boxes indicate alleles harboring the mutation (key: T, thymine; C, cytosine; W, wild-type; M, mutant). (B) Frontal and lateral photographs of the proband (III:1) taken at age 10 yrs, 7 mos. (C) Dental panoramic radiograph of the proband (III:1) taken at age 6 yrs, 6 mos.
