Table 4.

Univariate Odds Ratio (OR) Estimates for Predictors of Osteonecrosis of the Jaw, Overall and by Site

	Kaiser Permanente Northwest	HealthPartners	Overall
Predictor	OR (CI)	OR (CI)	OR (CI)
Any cancer	6.5 (2.5–16.9)	12.8 (2.4–70.1)	7.6 (3.4–17.3)
Osteoporosis	18.3 (6.8–49.4)	3.0 (0.4–25.9)	10.3 (4.2–25.0)
Diabetes	1.7 (0.5–5.8)	1.4 (0.2–11.9)	1.6 (0.5–4.6)
Immune disorder	16.3 (2.2–123.0)	—*	8.2 (1.1–61.0)
Head/neck radiation	11.4 (2.6–49.8)	24.3 (4.5–132.8)	14.2 (4.8–41.6)
Oral BPs	14.9 (5.5–40.3)	—*	9.2 (3.6–23.3)
Corticosteroids	2.8 (1.1–7.4)	3.4 (0.7–17.1)	3.0 (1.3–6.8)
Any risk factor	9.8 (2.8–34.3)	—*	13.4 (4.0–45.0)

OR = odds ratio, CI = confidence interval, BPs = bisphosphonates.

^*ORs could not be calculated due to zeros in the numerator for oral BPs and denominator for any risk factor.