Skip to main content
. Author manuscript; available in PMC: 2011 Jul 26.
Published in final edited form as: Toxicol Appl Pharmacol. 2008 Feb 6;229(3):265–272. doi: 10.1016/j.taap.2008.01.023

Figure 1. [14C]CH equivalents and total CH concentration in plasma of vehicle control and CD pretreated mice that received a challenge dose of [14C]CH.

Figure 1

Male C57BL16 mice were pretreated with corn oil, 5, or 15 mg CD/kg. [14C]CH (10 mg/kg in 5 ml/kg corn oil) was administered 3 days following pretreatment. Determinations were performed 4 and 16 h after ip administration of [14C]CH. [14C]CH equivalents of plasma and HDL were determined as described under “Material and methods”. Plasma total CH and HDLCH was determined enzymatically as described under “Material and Methods”. Non-HDL-CH content was taken as the difference between the total plasma CH and HDL-CH. A. [14C]CH equivalents of plasma 4 h after ip lipid bolus. B. [14C]CH equivalents of plasma 16 h after ip lipid bolus. C. Plasma total CH 4 h after ip lipid bolus. D. Plasma total CH 16 h after ip lipid bolus. Values are expressed mean ± SE(n=6 or 7). *Significantly different from the 4 h (p < 0.05).