FIG. 4.

Amino acid sequence alignment of representative Pam18 and Mdj2 orthologous proteins. Sequences were aligned using the Dialign-TX program, followed by manual inspection. Similar residues in each column are shaded. These representative sequences of Pam18 and Mdj2 orthologous proteins were derived from three Saccharomycotina fungi (post-WGD yeast, Saccharomyces cerevisiae; pre-WGD yeast, S. kluyveri; and Candida species, C. albicans) and three non-Saccharomycotina fungi (Schizosaccharomyces pombe from the subphylum Taphrinomycotina; Aspergillus fumigatus and Neurospora crassa from the subphylum Pezizomycotina).