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. Author manuscript; available in PMC: 2011 Jul 26.
Published in final edited form as: Am J Gastroenterol. 2009 Apr 14;104(5):1221–1230. doi: 10.1038/ajg.2009.121

Table 4.

Physical activity and sedentary behavior and the risk of uncomplicated diverticulosisa

Total Physical Activity, MET-h/wk (quintiles)b
1 2 3 4 5 P value for Trend
Casesc 224 306 340 345 300
Person years 68,701 75,740 79,510 81,197 80,962
Age-adjusted RRd 1.00 1.21 1.28 1.26 1.10 0.97
95% CI - 1.02–1.44 1.08–1.51 1.06–1.49 0.93–1.31
Multivariable RRe 1.00 1.05 1.07 1.04 0.93 0.36
95% CI - 0.88–1.24 0.90–1.27 0.88–1.24 0.78–1.12

Vigorous Physical Activity, MET-h/wk (quintiles)f
1 2 3 4 5 P value for Trend

Casesc 294 307 330 366 218
Person years 85,711 75,528 76,854 87,118 61,201
Age-adjusted RRd 1.00 1.11 1.18 1.19 1.05 1.00
95% CI - 0.94–1.30 1.01–1.38 1.02–1.39 0.88–1.25
Multivariable RRg 1.00 0.97 1.02 1.06 0.96 0.96
95% CI - 0.82–1.14 0.87–1.20 0.90–1.24 0.80–1.16

Non-Vigorous Physical Activity, MET-h/wk (quintiles)h
1 2 3 4 5 P value for Trend

Casesc 223 298 350 317 327
Person years 71,710 76,741 79,322 80,020 78,623
Age-adjusted RRd 1.00 1.25 1.37 1.19 1.23 0.45
95% CI - 1.05–1.49 1.16–1.62 1.00–1.42 1.03–1.46
Multivariable RRg 1.00 1.03 1.09 0.93 0.96 0.50
95% CI - 0.87–1.23 0.92–1.29 0.78–1.11 0.80–1.14

Sedentary Behavior, h/wk (quintiles)i
1 2 3 4 5 P value for Trend

Casesc 227 265 354 330 311
Person years 70,276 57,720 75,759 76,560 66,688
Age-adjusted RRd 1.00 1.27 1.43 1.34 1.40 0.0001
95% CI - 1.06–1.52 1.21–1.69 1.13–1.59 1.17–1.66
Multivariable RRj 1.00 1.18 1.34 1.25 1.29 0.008
95% CI - 0.99–1.42 1.13–1.59 1.05–1.48 1.08–1.54

MET, Metabolic Equivalent; RR, Relative Risk; CI, Confidence Interval

a

The analyses of uncomplicated diverticulosis were limited to men having undergone a lower endoscopy to reduce the risk of detection bias.

b

Quintiles of Total Physical Activity: ≤8.2, 8.3–19.0, 19.1–33.5, 33.6–57.3, ≥57.4

c

Cases numbers and person years may vary because of missing values.

d

Age-adjusted models include age in 1-year intervals and study period in 2-year intervals

e

Multivariable models include age, study period, sedentary behavior, BMI, use of NSAIDs, use of acetaminophen, dietary fat, fiber, red meat, combined nut, corn and popcorn consumption, and total calories.

f

Quintiles of Vigorous Physical Activity: 0, 0.1–4, 4.1–10, 10.1–28, ≥28.1

g

Models of vigorous activity adjust for non-vigorous activity and vice versa in addition to other covariates.

h

Quintiles of Non-vigorous Activity: 0–2.9, 3–7.9, 8–15.9, 16–29.9, ≥30

i

Quintiles of Sedentary Behavior: 0–15.9, 16–26.9, 27–38, 38.1–51.7, ≥51.8

j

Models of sedentary behavior are adjusted for total physical activity in addition to other covariates.