Table 1.
Aromatase mRNA expression and clinicopathologic factors in patients with invasive ductal carcinoma
| Factor | n | Aromatase mRNA (mean ± standard deviation) | P (Mann–Whitney U-test) |
| Age (years) | |||
| > 50 | 104 | 29 ± 60 | 0.0042* |
| ≤ 50 | 58 | 14 ± 24 | |
| Axillary lymph node status | |||
| - | 103 | 30 ± 62 | 0.010* |
| + | 59 | 13 ± 20 | |
| Tumor size | |||
| < 2 cm | 43 | 29 ± 54 | 0.042* |
| ≥ 2 cm | 119 | 22 ± 50 | |
| ER-α status | |||
| + | 108 | 28 ± 59 | 0.0021* |
| - | 47 | 13 ± 20 | |
| PgR status | |||
| + | 87 | 24 ± 44 | 0.63 |
| - | 62 | 25 ± 63 | |
| Histologic grade | |||
| 1 or 2 | 113 | 24 ± 50 | 0.11 |
| 3 | 49 | 24 ± 54 |
Estrogen receptor (ER)-α status and progesterone receptor (PgR) status were determined histochemically. *P < 0.05.