Table 2.
Seroconversion Rate (SCR) 14 and 21 Days After Administration of the Last Vaccine Dose
| SCR (95% CI)a |
|||
| Group and interval after last dose | A/Indonesia/5/2005 | A/Vietnam/1194/2004 | A/turkey/Turkey/1/2005 |
| 14 days | |||
| Group 0/21 (n = 65) | 96.9 (86.9–99.8) (n = 63) | 76.9 (64.8–86.5) (n = 50) | 83.1 (71.7–91.2) (n = 54) |
| Group 0/14 (n = 69) | 92.8 (81.2–98.3) (n = 64) | 59.4 (46.9–71.1) (n = 41) | 75.4 (63.5–84.9) (n = 52) |
| Group 0/7 (n = 74) | 71.6 (56.8–83.7) (n = 53) | 33.8 (23.2–45.7) (n = 25) | 51.4 (39.4–63.1) (n = 38) |
| Group 0/0 (n = 75) | 72.0 (57.3–83.9) (n = 54) | 33.3 (22.9–45.2) (n = 25) | 42.7 (31.3–54.6) (n = 32) |
| 21 days | |||
| Group 0/21 (n = 62) | 95.2 (86.5–99.0) (n = 59) | 66.1 (53.0–77.7) (n = 41) | 83.9 (72.3–92.0) (n = 52) |
| Group 0/14 (n = 69) | 92.8 (83.9–97.6) (n = 64) | 49.3 (37.0–61.6) (n = 34) | 71.0 (58.8–81.3) (n = 49) |
| Group 0/7 (n = 72) | 80.6 (69.5–88.9) (n = 58) | 26.4 (16.7–38.1) (n = 19) | 51.4 (39.3–63.3) (n = 37) |
| Group 0/0 (n = 74) | 74.3 (62.8–83.8) (n = 55) | 31.1 (20.8–42.9) (n = 23) | 50.0 (38.1–61.9) (n = 37) |
NOTE. Data are presented for according-to-protocol cohort (participants aged 18–64 years). Vaccine doses were administered at intervals of 21 days (group 0/21), 14 days (group 0/14), or 7 days (group 0/7) or on the same day (group 0/0). The SCR was defined as the percentage of participants with either a prevaccination titer <1:10 and a postvaccination titer ≥1:40 or a prevaccination titer ≥1:10 and a minimum 4-fold increase in postvaccination titer; n = number of participants with data available (stub column) or numbers of respondents (with SCR values).
For the A/Indonesia/5/2005 strain at 14 days, 98.75% confidence intervals (CIs) are shown; all other CIs are 95%.