Table 3.
Seroprotection Rate (SPR) 14 and 21 Days After Administration of the Last Vaccine Dose
| SPR (95% CI)a |
|||
| Group and interval after last dose | A/Indonesia/5/2005 | A/Vietnam/1194/2004 | A/turkey/Turkey/1/2005 |
| 14 days | |||
| Group 0/21 (n = 65) | 96.9 (86.9–99.8) (n = 63) | 78.5 (66.5–87.7) (n = 51) | 92.3 (83.0–97.5) (n = 60) |
| Group 0/14 (n = 69) | 92.8 (81.2–98.3) (n = 64) | 59.4 (46.9–71.1) (n = 41) | 82.6 (71.6–90.7) (n = 57) |
| Group 0/7 (n = 74) | 74.3 (59.7–85.9) (n = 55) | 35.1 (24.4–47.1) (n = 26) | 58.1 (46.1–69.5) (n = 43) |
| Group 0/0 (n = 75) | 74.7 (60.2–86.1) (n = 56) | 37.3 (26.4–49.3) (n = 28) | 52.0 (40.2–63.7) (n = 39) |
| 21 days | |||
| Group 0/21 (n = 62) | 95.2 (86.5–99.0) (n = 59) | 67.7 (54.7–79.1) (n = 42) | 93.5 (84.3–98.2) (n = 58) |
| Group 0/14 (n = 69) | 92.8 (83.9–97.6) (n = 64) | 49.3 (37.0–61.6) (n = 34) | 79.7 (68.3–88.4) (n = 55) |
| Group 0/7 (n = 72) | 81.9 (71.1–90.0) (n = 59) | 30.6 (20.2–42.5) (n = 22) | 61.1 (48.9–72.4) (n = 44) |
| Group 0/0 (n = 74) | 77.0 (65.8–86.0) (n = 57) | 36.5 (25.6–48.5) (n = 27) | 58.1 (46.1–69.5) (n = 43) |
NOTE. Data are presented for according-to-protocol cohort (participants aged 18–64 years). Vaccine doses were administered at intervals of 21 days (group 0/21), 14 days (group 0/14), or 7 days (group 0/7) or on the same day (group 0/0). The SPR was defined as the attainment rate for reciprocal hemagglutination inhibition titers ≥40; n = number of participants with data available (stub column) or numbers of respondents (with SPR values).
a
For the A/Indonesia/5/2005 strain at 14 days, 98.75% confidence intervals (CIs) are shown; all other CIs are 95%.