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. 2011 Jul 26;6(7):e22047. doi: 10.1371/journal.pone.0022047

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Chew et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) The SPARC to vimentin ratio was significantly greater in CRC tissue compared to normal colonic tissue. (B) No difference in SPARC expression was observed between stage II and III CRC. (C) SPARC was significantly greater in patients with a good disease outcome in stage II CRC, but not in (D) stage III CRC. Each dot represents one patient and the bars represent the median value ± SEM.