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. 2011 Jul 26;6(7):e22510. doi: 10.1371/journal.pone.0022510

Figure 4. Effects of shikonin on oxygen consumption.

Figure 4

(A) Oxygen consumption measurements in L6 myotubes. Representative graph from three independent measurements of oxygen consumption in L6 myotubes.1 µM shikonin was added as indicated. (B) Shikonin stimulated increase in oxygen consumption in L6 myotubes expressed as percentage of basal. Graphs show mean ± SEM from three independent experiments. (C) Oxygen consumption in mitochondria from skeletal muscle in response to shikonin was measured in the absence (thin line) or presence (bold line) of pyruvate. 10 µM shikonin was added as indicated.