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. 2011 Jul 26;6(7):e22618. doi: 10.1371/journal.pone.0022618

Table 4. Adjusted odds ratios for hospitalization and death by prior and current influenza immunization status.

Adjusted a odds ratio (95% CI)
Two year prior immunization history; current immunization Fall Pre-Influenza Influenza Summer
Hospitalizations b
None; unimmunized Ref Ref Ref Ref
None; immunized 1.34 (1.00, 1.78) 1.38 (1.10, 1.74) 1.29 (1.12, 1.49) 1.35 (1.14, 1.60)
One; unimmunized 1.66 (1.25, 2.20) 1.29 (1.04, 1.61) 1.24 (1.06, 1.47) 1.29 (1.06, 1.57)
One; immunized 0.73 (0.56, 0.94) 1.1 (0.90, 1.29) 1.10 (0.97, 1.25) 0.99 (0.86, 1.15)
Two; unimmunized 2.34 (1.82, 2.99) 1.41 (1.14, 1.73) 1.21 (1.03, 1.43) 1.01 (0.80, 1.27)
Two; immunized 0.60 (0.48, 0.75) 0.89 (0.76, 1.04) 0.77 (0.69, 0.86) 0.78 (0.68, 0.90)
Deaths (All-cause)
None; unimmunized n/a Ref Ref Ref
None; immunized n/a 0.76 (0.65,0.89) 0.94 (0.84, 1.05) 1.07 (0.67, 1.18)
One; unimmunized n/a 1.73 (1.57,1.92) 1.66 (1.51, 1.82) 1.30 (1.17, 1.45)
One; immunized n/a 0.68 (0.60,0.76) 0.89 (0.81, 0.96) 1 (0.92, 1.09)
Two; unimmunized n/a 2.45 (2.21,2.72) 1.78 (1.61, 1.96) 1.35 (1.21, 1.51)
Two; immunized n/a 0.58 (0.53,0.64) 0.71 (0.66, 0.77) 0.79 (0.73, 0.85)

Note. CI = confidence interval. 2003–04 could not contribute to pre-influenza period for hospitalizations and was excluded from all periods for mortality owing to early start to influenza season that year.

a

Adjusted for age, prior pneumococcal immunization, and medical visits prior year.

b

Pneumonia, influenza, or acute respiratory disease listed as most responsible admission diagnosis.