Figure 5.

Spatial discrimination reversal learning. Ethanol-exposed subjects were not impaired on the initial position discrimination, as shown by the mean (± SEM) number of trials to the first success (A); however, they were unable to achieve the same number of successful discrimination reversals as maltose controls, committing significantly more errors. Specifically, ethanol-exposed subjects committed significantly more perseverative-type errors than MC animals (mean ± SEM perseverative-type errors committed during testing (B)). Memantine treatment did not significantly improve performance in the ethanol-treated subjects, or have a significant effect on control subjects.

* ethanol-exposed groups differed significantly from controls