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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: Exp Hematol. 2011 May 13;39(8):837–849. doi: 10.1016/j.exphem.2011.05.005

Figure 5.

Figure 5

IFN-γ deficiency reduces immune-mediated BM failure. Infusion of LN cells from B6 mice that carry germline deletion of the IFN-γ gene (IFN-γ−/− LN) into sublethally-irradiated C.B10 hosts (n=6) showed no expansion of MHC class II+Fas+ cells in recipient BM in comparison to TBI-only (n=4) controls. Levels of total BM cells, blood neutrophils, red blood cells and platelets were not different between IFN-γ−/− LN cell-infused animals and TBI-only controls.