Table 1.
Baseline demographic, clinical, and laboratory values in study participants
| Dietary Omega-3 Intake | ||||||
|---|---|---|---|---|---|---|
| Quartile of Omega-3 intake | P for trend |
|||||
| All Patients | 1 (0.1<0.8 mg/d) |
2 (0.8-<1.1 mg/d) |
3 (1.1-<1.6 mg/d) |
4 (1.6-3.5 mg/d) |
||
| No. | 145 | 37 | 36 | 37 | 35 | |
| Age, years | 53±14 | 52±15 | 52±15 | 54±14 | 53±12 | 0.8 |
| Women | 43 | 51 | 42 | 40 | 37 | 0.2 |
| African-American | 42 | 32 | 45 | 38 | 54 | 0.1 |
| History of hypertension | 16 | 16 | 18 | 11 | 17 | 0.8 |
| Diabetes mellitus | 55 | 51 | 55 | 57 | 57 | 0.5 |
| Charlson comorbidity score | 1.9±1.7 | 1.6±1.5 | 2.0±1.6 | 2.2±2.0 | 1.9±1.5 | 0.8 |
| Body mass index, kg/m2 | 26.1±5.9 | 24.5±4.4 | 27.5±7.4 | 26.9±5.9 | 25.6±5.0 | 0.4 |
| Percentage body fat* | 25.5±10.2 | 24.5±10.0 | 27.2±11.2 | 26.2±10.0 | 24.0±9.6 | 0.6 |
| Dialysis vintage, months | 31±33 | 29±27 | 36±36 | 31±34 | 29±35 | 0.7 |
| Dialysis dose, spKt/Vurea | 1.67±0.30 | 1.68±0.33 | 1.71±0.28 | 1.63±0.25 | 1.64±0.35 | 0.2 |
| Serum albumin, g/dl | 3.97±0.31 | 3.91±0.32 | 4.02±0.21 | 4.02±0.22 | 4.04±0.31 | 0.07 |
| Serum creatinine, mg/dl | 10.7±3.2 | 10.6±2.7 | 10.7±3.1 | 10.6±3.5 | 11.0±3.5 | 0.4 |
| Serum total homocysteine, μmol/l | 25.6±8.7 | 25.3±10.2 | 25.4±8.1 | 24.0±8.7 | 27.6±7.6 | 0.3 |
| Serum CRP, mg/l | 5.4±7.3 | 5.1±5.1 | 7.0±11.6 | 5.1±5.3 | 4.4±4.4 | 0.6 |
| Serum IL-6, pg/ml | 18.4±60.9 | 11.7±16.6 | 30.0±27.0 | 12.7±31.0 | 18.8±37.3 | 0.6 |
| Serum TNF-α , pg/ml | 7.4±7.7 | 7.0±6.8 | 7.5±6.5 | 9.0±11.2 | 5.8±4.7 | 0.4 |
| Dietary Omega-6 to Omega-3 Ratio | |||||
|---|---|---|---|---|---|
| Quartile of Omega-6 to Omega-3 Ratio | P for trend |
||||
| 1 (1.7-<7.6) |
2 (7.6-<9.3) |
3 (9.3-<11.3) |
4 (11.3-17.4) |
||
| No. | 37 | 36 | 36 | 36 | |
| Age, years | 55±12 | 53±15 | 53±13 | 50±14 | 0.1 |
| Women | 43 | 47 | 42 | 39 | 0.6 |
| African-American | 32 | 47 | 53 | 39 | 0.5 |
| History of hypertension | 11 | 19 | 11 | 19 | 0.5 |
| Diabetes mellitus | 62 | 56 | 53 | 50 | 0.3 |
| Charlson comorbidity score | 1.8±1.4 | 2.1±1.8 | 1.7±1.8 | 1.8±1.6 | 0.6 |
| Body mass index, kg/m2 | 25.6±5.2 | 26.5±6.4 | 27.2±6.0 | 25.2±6.2 | 0.6 |
| Percentage body fat* | 26.1±10.1 | 26.6±10.4 | 25.8±10.5 | 23.9±9.9 | 0.3 |
| Dialysis vintage, months | 19.6±15.5 | 27.5±42.4 | 33.1±40.6 | 34.5±25.5 | 0.01 |
| Dialysis dose, spKt/Vurea | 1.7±0.3 | 1.7±0.3 | 1.6±0.2 | 1.6±0.3 | 0.3 |
| Serum albumin, g/dl | 3.96±0.32 | 3.96±0.32 | 3.98±0.22 | 3.98±0.25 | 0.7 |
| Serum creatinine, mg/dl | 10.5±3.8 | 11.0±3.3 | 10.7±3.2 | 11.0±2.5 | 0.6 |
| Serum total homocysteine, μmol/l | 26.8±7.9 | 25.4±7.8 | 25.1±9.1 | 24.6±9.1 | 0.1 |
| Serum CRP, mg/l | 3.8±3.3 | 4.2±3.7 | 8.2±12.2 | 5.1±6.0 | 0.4 |
| Serum IL-6, pg/ml | 25.5±10.7 | 25.1±25.3 | 13.9±23.7 | 8.2±8.6 | 0.4 |
| Serum TNF-α , pg/ml | 6.3±3.9 | 9.3±12.9 | 6.3±4.0 | 7.8±6.7 | 0.5 |
Note: values shown are percentage or mean +/− SD.
*
measured by NIR interactance
Abbreviations: IL-6: interleukin-6, TNF: tumor necrosis factor; CRP, C-reactive protein.
Conversion factors for units: albumin in g/dL to g/L, ×10; creatinine in mg/dL to umol/L, ×88.4; total homocysteine in umol/L to mg/dL, ×0.14.