Table 3.

Cross-sectional association between CSF lipids and other cognitive test z-scores

Log lipid	Rey-Osterrieth Complex Figure Test—Copy		Rey-Osterrieth Complex Figure Test—Recall		Odd Man Out		Verbal Fluency
	b	p value	b	p value	b	p value	b	p value
Total SM	−0.34	0.593	0.09	0.756	−0.03	0.941	−0.23	0.375
Total Cholesterol	0.10	0.943	0.52	0.403	0.48	0.549	−0.31	0.591
SM/Cholesterol	−0.80	0.357	−0.12	0.745	−0.19	0.722	−0.35	0.335
Ceramide C16:0	−0.96	0.500	−0.28	0.666	−0.83	0.265	−0.21	0.728
Ceramide C18:0	0.09	0.928	0.73	0.077	0.23	0.644	0.44	0.251
Ceramide C22:0	−1.56	0.231	0.36	0.550	−1.07	0.110	0.15	0.791
Ceramide C24:0	−0.94	0.115	0.07	0.788	−0.14	0.655	−0.08	0.769
SM/Ceramide C16:0	−0.39	0.505	−0.02	0.939	0.19	0.620	−0.25	0.299
SM/Ceramide C18:0	−0.48	0.381	−0.41	0.086	0.09	0.774	−0.31	0.159
SM/Ceramide C22:0	0.00	1.000	0.01	0.978	0.57	0.263	−0.31	0.339
SM/Ceramide C24:0	0.74	0.297	−0.03	0.917	0.16	0.696	−0.14	0.652
	Digit Symbol		Grooved Pegboard Dominant Hand		Mean Choice Reaction Time		Mean Sequential Reaction Time
Log lipid	b	p value	b	p value	b	p value	b	p value
Total SM	−0.03	0.915	−0.47	0.478	0.09	0.778	0.03	0.939
Total Cholesterol	0.08	0.902	0.78	0.595	0.21	0.766	−0.49	0.550
SM/Cholesterol	−0.14	0.724	−1.16	0.208	0.00	0.997	0.12	0.810
Ceramide C16:0	−1.06	0.098	−1.83	0.225	−0.63	0.307	−0.51	0.477
Ceramide C18:0	0.17	0.685	0.30	0.763	0.24	0.533	0.31	0.521
Ceramide C22:0	−0.62	0.301	−1.57	0.260	−0.44	0.477	−0.10	0.888
Ceramide C24:0	−0.18	0.509	−1.14	0.068	−0.19	0.474	0.08	0.802
SM/Ceramide C16:0	0.08	0.776	−0.28	0.656	0.11	0.723	−0.06	0.870
SM/Ceramide C18:0	−0.23	0.346	−0.11	0.851	−0.21	0.402	−0.41	0.173
SM/Ceramide C22:0	0.19	0.596	−0.09	0.912	0.38	0.384	0.12	0.802
SM/Ceramide C24:0	0.22	0.499	0.73	0.334	0.43	0.193	−0.10	0.804