FIG. 5.

VCAM-1 expression was measured in mice treated with tempol. Tempol treatment, regardless of mode of administration, had no effect on VCAM-1 expression in either the upstream region or the downstream region when compared to the control. Representative confocal images from en face mounted aortas stained for VCAM-1 are presented. A, C, and E are from the upstream region; B, D, and F are from the downstream region from a coarctation aorta; A and B are from control mice; C and D.are from mice treated with tempol administered by drinking water; E and F are from mice treated with tempol administered by mini-pump. N = 6–8, *p < 0.05 comparing upstream region to downstream region. (To see this illustration in color the reader is referred to the web version of this article at www.liebertonline.com/ars).