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. 2011 Jun 9;12:81. doi: 10.1186/1471-2350-12-81

Table 1.

Allelic and genotypic frequencies of -1082G > A and -592C > A IL-10 gene promoter variants

Males Females

Control
(n = 201)
Schizophrenia
(n = 153)
OR (95%CI) P Control
(n = 234)
Schizophrenia
(n = 88)
OR (95% CI) P

Age (years) 37 ± 18 45 ± 13 0.000* 39 ± 18 46 ± 13 0.002*
-1082G > A
Allelic frequencies
n % n % p n % n %
G 164 40.8% 111 36.3% 1.21 (0.88-1.66) 0.252 198 42.3% 57 32.4% 1.53 (1.04-2.25) 0.027*
A 238 59.2% 195 63.7% 270 57.7% 119 67.6%
Genotypic frequencies
G/G 38 18.9% 23 15.0% 0.502 33 14.1% 11 12.5% 0.008*
G/A 88 43.8% 65 42.5% 132 56.4% 35 39.8%
A/A 75 37.3% 65 42.5% 69 29.5% 42 47.7%

-592 C > A
Allelic frequencies
n % n % OR (95%CI) p n % n % OR (95% CI) p
C 274 75.7% 227 72.8% 1.11 (0.77-1.60) 0.618 298 74.5% 123 69.1% 0.76 (0.51-1.15) 0.213
A 88 24.3% 79 25.3% 102 25.5% 53 29.8%
Genotypic frequencies
C/C 110 60.8% 84 53.8% 0.134 106 53.0% 47 52.8% 0.004*
C/A 54 29.8% 59 37.8% 86 43.0% 29 32.6%
A/A 17 9.4% 10 6.4% 8 4.0% 12 13.5%