Figure 5.
The insertion region (gray box) of SpUP is revealed by the alignment of SpUP against EcUP and EcPNP. Magenta, green, and orange triangles indicate conserved residues in the phosphate-binding site, ribose-binding site, and uracil-binding site of SpUP, respectively. The residues marked with an asterisk are the two novel residues found in the uracil-binding site of SpUP.