Table 1.
Demographic and Clinical Characteristics of Subjects
| Factor | All (N=208) |
Ultrasound 2-3 (N=123) |
Ultrasound 0-1 (N=85) |
p-value |
|---|---|---|---|---|
| Male [n (%)] | 132 (63.5) | 85 (69.1) | 47 (55.3) | 0.042 |
| Age at first visit (yr) | 10.8 ± 2.5 | 11.2 ± 2.3 | 10.2 ± 2.6 | 0.005 |
| Weight (kg) | 55.4 ± 16.3 | 59.1 ± 16.8 | 50.0 ± 14.0 | <0.001 |
| Height (cm) | 145.5 ± 16.0 | 148.5 ± 15.8 | 141.2 ± 15.3 | <0.001 |
| BMI (kg/m2) | 25.3 ± 3.9 | 26.0 ± 3.8 | 24.3 ± 3.7 | 0.002 |
| BMI Percentile | 94.3 ± 6.6 | 95.1 ± 5.3 | 93.1 ± 7.9 | 0.046 |
| WC (cm) | 86.5 ± 10.0 | 88.6 ± 9.3 | 83.6 ± 10.3 | <0.001 |
| WC Percentile | 93.8 ± 3.7 | 94.3 ± 3.6 | 93.0 ± 3.8 | 0.014 |
| Systolic BP (mmHg) | 111.6 ± 12.9 | 111.8 ± 12.7 | 111.4 ± 13.3 | 0.83 |
| Diastolic BP (mmHg) | 68.5 ± 8.5 | 68.9 ± 8.6 | 67.8 ± 8.4 | 0.39 |
| Cholesterol (mg/dL) | 162.8 ± 34.2 | 165.4 ± 35.4 | 159 ± 32.3 | 0.17 |
| Triglycerides (mg/dL) | 90.0 (71, 127) | 90 (75, 130) | 90 (69, 120) | 0.37 |
| ALT (U/L) | 69.5 (50.0, 87.0) | 69.0 (51.0, 93.0) | 71.0 (49.0, 84.0) | 0.5 |
| AST (U/L) | 48.5 (39.0, 62.0) | 49.0 (39.0, 65.0) | 47.0 (39.0, 58.0) | 0.41 |
| GGT (U/L) | 25.0 (18.0, 38.0) | 27.0 (20.0, 41.0) | 22.0 (17.0, 32.0) | 0.01 |
| Total bilirubin (mg/dL) | 0.6 ± 0.2 | 0.6 ± 0.2 | 0.7 ± 0.2 | 0.09 |
| Albumin (g/dL) | 4.5 ± 0.5 | 4.5 ± 0.5 | 4.6 ± 0.6 | 0.58 |
| Alkaline phosphatase (U/L) | 720.9 ± 190.9 | 772.4 ± 205.0 | 652.2 ± 145.5 | <0.001 |
| ISI (M/mU/L) | 4.0 ± 2.2 | 3.8 ± 2.1 | 4.2 ± 2.2 | 0.15 |
| QUICKI | 0.3 ± 0.0 | 0.3 ± 0.0 | 0.3 ± 0.0 | 0.06 |
Values presented as Mean ± SD or Median (25th, 75th percentiles) for continuous factors and N (%) for categorical variables.
p-values correspond to t-tests or Wilcoxon rank sum tests for continuous factors,Pearson’s chi-square tests for categorical variables and Mantel-Haenszel chi-square tests for histology and ultrasound scores.