Table 2.
The relationship between endoplasmic reticulum stress-associated molecules and cartilage degeneration
| Mild | Moderate | Severe | Mankin score | ||
|---|---|---|---|---|---|
| (n = 5) | (n = 7) | (n = 8) | rs | P-value | |
| pPERK (%) | 23.0 ± 10.4 | 37.0 ± 5.0 | 49.0 ± 7.0*† | 0.86 | 0.001 |
| Ub (%) | 19.1 ± 2.8 | 29.6 ± 6.6 | 59.3 ± 3.7*† | 0.81 | 0.001 |
| GRP78 (%) | 16.2 ± 2.9 | 21.2 ± 1.9 | 24.2 ± 2.8 | 0.51 | 0.028 |
| CHOP (%) | 8.2 ± 5.2 | 15.9 ± 13.7 | 35.4 ± 9.2*† | 0.74 | 0.002 |
| pJNK (%) | 8.6 ± 7.5 | 32.7 ± 14.9* | 48.6 ± 13.8* | 0.81 | 0.001 |
rs, Spearman's rank correlation coefficient.
The values are expressed as mean ± SEM.
*
P < 0.05 vs. mild
†
P < 0.05 vs. moderate.