Table 1.

Effects of chronic early lead (Pb) exposure (320 ppm, prenatal and postnatal) on the Pb levels in blood and brain regions of rats of 90 days of age

	Concentration of Pb
Sample	Control group	Pb-exposed group
Blood (μg/dl)	2.1 ± 0.2	29.5 ± 1.9*
Frontal cortex (μg/g tissue)	6.6 ± 0.3	69.1 ± 3.0*
Hypothalamus (μg/g tissue)	7.8 ± 0.3	65.5 ± 3.8*
Hippocampus (μg/g tissue)	4.7 ± 0.3	53.8 ± 1.9*†

Data were obtained from five animals per group and are expressed as means ± SEM.

^*Statistically significant difference compared with control group, P < 0.001, one-way anova.

^†Statistically significant difference when compared to prefrontal cortex and hypothalamus of the group exposed to Pb.