Table 1.

Reported cardiovascular and metabolic functions of GPER1

Tissue/cell	GPER1 regulatory function	Reference
Vascular smooth muscle cell	Antiproliferation	Haas et al. (2009)
Vascular smooth muscle	Endothelium-dependent relaxation	Lindsey et al. (2009)
Vascular smooth muscle	Endothelium-dependent relaxation	Broughton et al. (2010)
Vascular smooth muscle	Relaxation	Haas et al. (2009)
Vascular endothelium	Decreased superoxide production	Broughton et al. (2010)
Vascular endothelium	No effects on aortic eNOS mRNA and serum nitric oxide levels	Lindsey et al. (2009)
Endothelial cell	Antiproliferation	Holm et al. (2011)
Pancreatic β-cell	Insulin release	Mårtensson et al. (2009); Balhuizen et al. (2010)
Pancreatic β-cell	Anti-apoptosis	Balhuizen et al. (2010); Liu et al. (2009)

GPER1, G protein-coupled oestrogen receptor 1.