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Summary of pharmacokinetic data for compound B obtained from rats
| Dose | |||
|---|---|---|---|
| 3 mg·kg−1 | 10 mg·kg−1 | 30 mg·kg−1 | |
| Blood concentration (µM) | 0.47 ± 0.16 | 2.08 ± 0.45 | 3.79 ± 0.79 |
| Brain concentration (µM) | 4.29 ± 1.05 | 15.99 ± 2.30 | 26.78 ± 2.00 |
| Brain : blood ratio | 9.3 ± 1.8 | 7.9 ± 1.9 | 7.3 ± 1.2 |
Data are mean ± SD of seven observations.
