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. Author manuscript; available in PMC: 2012 Jun 21.
Published in final edited form as: Circulation. 2011 May 31;123(24):2811–2818. doi: 10.1161/CIRCULATIONAHA.110.009928

Table 3.

Univariable association between baseline characteristics of diabetic and non-diabetic women and a detectable high-sensitivity cardiac troponin T (≥0.003 μg/L) at baseline in the Women’s Health Study.

Diabetic Women* Reference Subcohort of Non-Diabetic Women† Test for Difference in Association
Characteristic Odds Ratio (95% CI) P-value Odds Ratio (95% CI) P-value P-value
Age, per 5 year increase 1.18 (1.05-1.32) 0.006 1.35 (1.21-1.51) <0.0001 0.09
White race (as compared to non-White race) 0.85 (0.49-1.46) 0.55 1.38 (0.68-2.79) 0.37 0.29
History of hypertension 1.80 (1.24-2.61) 0.002 1.78 (1.22-2.60) 0.0026 0.97
Systolic Blood Pressure, per 10 mmHg increase 1.28 (1.12-1.45) 0.0002 1.22 (1.08-1.37) 0.0009 0.60
Treatment for hypertension 1.33 (0.93-1.88) 0.12 1.60 (1.01-2.52) 0.05 0.53
Current smoking‡ 0.93 (0.53-1.65) 0.81 0.39 (0.18-0.83) 0.015 0.07
Past smoking‡ 1.20 (0.82-1.75) 0.35 0.90 (0.61-1.31) 0.57 0.29
History of cholesterol > 240 mg/dL 0.94 (0.66-1.32) 0.70 1.30 (0.89-1.89) 0.17 0.21
Treatment for high cholesterol 1.38 (0.80-2.38) 0.24 0.76 (30-1.94) 0.56 0.28
Parental history of myocardial infarction at age <60y 0.76 (0.44-1.29) 0.31 0.98 (0.56-1.72) 0.95 0.51
Body mass index (per 1 kg/m2 increase) 1.02 (0.99-1.05) 0.32 1.03 (1.00-1.07) 0.07 0.47
Total cholesterol (per 1 SD increase) 1.24 (1.06-1.44) 0.008 0.84 (0.70-1.01) 0.06 0.002
LDL cholesterol (per 1 SD increase) 1.21 (1.03-1.42) 0.02 0.92 (0.76-1.10) 0.35 0.03
HDL cholesterol (per 1 SD increase) 1.01 (0.84-1.21) 0.92 0.87 (0.73-1.05) 0.15 0.28
Natural logarithm of hsCRP (per 1 SD increase) 1.01 (0.84-1.21) 0.93 1.09 (0.91-1.31) 0.35 0.55
Fibrinogen (per 1 SD increase) 1.14 (0.99-1.32) 0.07 1.22 (1.02-1.46) 0.03 0.57
Hemoglobin A1c (per 1 SD increase) 1.05 (1.02-1.08) 0.003 1.28 (1.07-1.53) 0.007 0.03
Natural logarithm of the EGFR (per 1 SD increase) 1.12 (0.96-1.32) 0.16 0.91 (0.76-1.09) 0.32 0.09
Natural logarithm of NT-proBNP (per 1 SD increase) 1.28 (1.08-1.52) 0.004 1.17 (0.98-1.40) 0.09 0.46
Natural logarithm of Lp(a) (per 1 SD increase) 1.07 (0.92-1.25) 0.39 1.01 (0.84-1.21) 0.94 0.61
*

Of the 512 diabetic women, 233 (45.5%) had a detectable hsTnT.

†

Of the 564 non-diabetic women in the reference subcohort, 171 (30.3%) had a detectable hsTnT.

‡

Current and past smokers are included in the same logistic regression model, such that never smokers are the referent group.

Abbreviations: EGFR, estimated glomerular filtration rate; HDL, high-density lipoprotein cholesterol; hsCRP, high sensitivity C-reactive protein; LDL, low-density lipoprotein cholesterol; Lp(a), lipoprotein (a); SD, standard deviation