Table 3.

Reaction of various indole based aldehydes with Rhodanine derivatives

Entry (%)	R1	R2	R3	R4	product	Yielda,b
1	H	H	H	H	7a	95
2	CH3	H	H	H	7b	96
3	CH3	CH3	H	H	7c	90
4	CH3	H	H	OCH3	7d	93
5	OCH3	H	H	H	7e	95
6	OCH3	H	H	OCH3	7f	92
7	H	H	H	OCH3	7g	94
8	CN	H	H	OCH3	7h	90
9	CN	H	H	H	7i	91
10	H	H	H	Cl	7j	89
			H	H	7k	95
			H	OCH3	7l	93
			H	CN	7m	91
14	OH	Br	Br	H	7n	90
15	OH	Cl	Cl	H	7o	89
16	OH	Br	Br	OCH3	7p	96
17	OH	Cl	Cl	OCH3	7q	90

^aIsolated yield;

^bAll the compounds were characterized by ¹H NMR, ¹³C NMR, DEPT-135, IR and HRMS analysis.