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. 2003 Nov 25;6(1):R38–R45. doi: 10.1186/bcr745

Table 2.

Tumor and serum basic fibroblast growth factor (bFGF) in relation to clinical, pathological and biological characteristics in breast cancer patients

Tumor bFGF Serum bFGF

Number of cases % positive cells [median (range)] P Number of cases Serum level (pg/ml) [median (range)] P
Age
 51–70 years 41 45 (0–90) 0.25 46 2.2 (0.3–15.1) 0.40
 > 70 years 22 65 (5–100) 27 3.0 (0.4–26.6)
Histotype
 Ductal 54 55 (0–100) 0.68 60 2.2 (0.3–26.6) 0.90
 Others 9 60 (0–85) 13 2.3 (0.4–5.2)
Tumor size
 ≤ 2 cm 43 55 (5–100) 0.53 51 2.3 (0.3–26.6) 0.37
 > 2 cm 20 63 (5–100) 21 1.9 (0.4–11.1)
Node status
 Node-negative 30 63 (0–100) 0.69 35 2.5 (0.3–15.1) 0.43
 Node-positive 27 65 (0–100) 28 2.0 (0.5–26.6)
Grade
 1–2 38 62.5 (0–100) 0.99 42 2.3 (0.3–15.1) 0.57
 3 12 60 (5–100) 13 3.1 (1.5–26.6)
Steroid status
 ER-positive 43 45 (0–100) 0.43 49 2.2 (0.3–15.1) 0.32
 ER-negative 10 65 (5–95) 11 3.5 (1.8–11.1)
 PgR-positive 32 38 (0–100) 0.12 35 2.0 (0.4–8.6) 0.19
 PgR-negative 21 70 (5–95) 25 2.5 (0.3–15.1)

ER, estrogen receptor; PgR, progesterone receptor.