Table 2.
Tumor and serum basic fibroblast growth factor (bFGF) in relation to clinical, pathological and biological characteristics in breast cancer patients
| Tumor bFGF | Serum bFGF | |||||
| Number of cases | % positive cells [median (range)] | P | Number of cases | Serum level (pg/ml) [median (range)] | P | |
| Age | ||||||
| 51–70 years | 41 | 45 (0–90) | 0.25 | 46 | 2.2 (0.3–15.1) | 0.40 |
| > 70 years | 22 | 65 (5–100) | 27 | 3.0 (0.4–26.6) | ||
| Histotype | ||||||
| Ductal | 54 | 55 (0–100) | 0.68 | 60 | 2.2 (0.3–26.6) | 0.90 |
| Others | 9 | 60 (0–85) | 13 | 2.3 (0.4–5.2) | ||
| Tumor size | ||||||
| ≤ 2 cm | 43 | 55 (5–100) | 0.53 | 51 | 2.3 (0.3–26.6) | 0.37 |
| > 2 cm | 20 | 63 (5–100) | 21 | 1.9 (0.4–11.1) | ||
| Node status | ||||||
| Node-negative | 30 | 63 (0–100) | 0.69 | 35 | 2.5 (0.3–15.1) | 0.43 |
| Node-positive | 27 | 65 (0–100) | 28 | 2.0 (0.5–26.6) | ||
| Grade | ||||||
| 1–2 | 38 | 62.5 (0–100) | 0.99 | 42 | 2.3 (0.3–15.1) | 0.57 |
| 3 | 12 | 60 (5–100) | 13 | 3.1 (1.5–26.6) | ||
| Steroid status | ||||||
| ER-positive | 43 | 45 (0–100) | 0.43 | 49 | 2.2 (0.3–15.1) | 0.32 |
| ER-negative | 10 | 65 (5–95) | 11 | 3.5 (1.8–11.1) | ||
| PgR-positive | 32 | 38 (0–100) | 0.12 | 35 | 2.0 (0.4–8.6) | 0.19 |
| PgR-negative | 21 | 70 (5–95) | 25 | 2.5 (0.3–15.1) | ||
ER, estrogen receptor; PgR, progesterone receptor.