Figure 2.
Western immunoblots showing the effect of FSH and/or RANK-L on the phosphorylation of Akt (p-Akt), Erk (p-Erk) or JNK (p-JNK) measured in total cell lysates (panels: A and B) (loading control: actin), or on c-fos and c-jun measured in nuclear extracts (loading control: lamin B1) in RAW264.7 cells (panels: Ca to Cc) in the presence or absence of pertussis toxin (PTX). Western immunoblots for c-fos and c-jun in cells isolated from bone marrow precursors derived from FSH receptor null mice (FSHR-/-) and wild type littermates (FSHR+/+) (panel: Cd).