Table 1.
Frequency of nonmotor symptoms. In the NMS-Q, at least 1 question in the category is “yes.” In the NMS-S, Severity “Frequency” is greater than 0 in at least 1 item in the subgroups.
| NMS-Q | Patient evaluation | Caregiver evaluation | Correlation | P value |
|---|---|---|---|---|
| Percent prevalence | Percent prevalence | |||
| Gastrointestinal | 87.9% | 81.8% | 0.53 | 0.002 |
| Sleep | 84.9% | 90.9% | 0.62 | 0.0001 |
| Urinary | 72.7% | 63.6% | 0.62 | 0.0001 |
| Miscellaneous* | 69.7% | 69.7% | 0.54 | 0.001 |
| Cognition | 63.6% | 66.7% | 0.46 | 0.007 |
| Sexual | 54.6% | 57.1% | 0.42 | 0.03 |
| Cardiovascular/falls | 54.6% | 42.4% | 0.36 | 0.04 |
| Mood | 48.5% | 54.6% | 0.65 | 0 < .0001 |
| Perceptual** | 18.2% | 15.2% | 0.46 | 0.007 |
| NMS-S | Patient evaluation | Caregiver evaluation | Correlation | P value |
| Percent prevalence | Percent prevalence | |||
| Sleep/Fatigue | 90.9% | 93.9% | 0.46 | 0.01 |
| Gastrointestinal | 75.8% | 72.7% | 0.48 | 0.005 |
| Mood | 75.8% | 72.7% | 0.55 | 0.0009 |
| Miscellaneous*** | 72.7% | 66.7% | 0.38 | 0.03 |
| Cognition | 60.6% | 69.7% | 0.62 | 0.0001 |
| Urinary | 57.6% | 48.5% | 0.47 | 0.01 |
| Sexual | 45.5% | 53.6% | 0.50 | 0.01 |
| Cardiovascular/falls | 45.5% | 33.3% | 0.39 | 0.02 |
| Perceptual**** | 18.2% | 15.2% | 0.40 | 0.02 |
*Refers to miscellaneous subset in NMS-Q that includes questions about change in smell, unexplained pain, unexplained weight change, swelling of legs, and excessive sweating.
**Refers to perceptual subset in NMS-Q that includes questions about diplopia and delusional thoughts.
***Refers to miscellaneous subset in NMS-S that includes questions about unexplained pain, change in smell, unexplained weight change, and excessive sweating.
****Refers to perceptual subset in NMS-S that includes questions about hallucinations, delusional beliefs, and diplopia.