Fig. 3.

Mean (± SEM) plasma glucagon, glucose-dependent insulinotropic polypeptide (GIP), and glucagon-like peptide-1 (GLP-1) concentrations and incremental areas under the curves (iAUC) for a meal test day (week 10) in two groups who received supplementation containing either sucrose (♦), n=12 or artificial sweeteners (□), n=11 for 10 weeks in addition to their habitual diet. Postprandial responses were tested by repeated measurement analysis. For all curves, the time effect was significant (P<0.0001). No differences were seen for GIP. For postprandial glucagon and GLP-1, there were significant group differences (p<0.05 and P<.0001, respectively), but no differences in iAUC.