Table 4.

Predictors of distress in both male and female BRCA1/2 carriers

Variable	6-Months outcomes Z scores			12-Months outcomes Z scores
	Cancer-specific distress	General distress	Genetic-testing distress	Cancer-specific distress	General distress	Genetic-testing distress
Associated baseline variablea
Men	3.66***	1.77c	3.37***	4.44***	2.74**	4.73***
Women	6.30***	3.58***	4.77***	6.22***	3.09**	3.22**
Family history totalb
Men	0.85	0.73	0.30	−1.54	0.09	1.26
Women	1.62c	1.88c	0.13	0.71	−0.26	−0.37
Having daughters (vs. not)
Men	0.08	1.38	1.42	0.46	0.10	1.76c
Women	1.04	0.25	0.06	1.43	−0.07	−0.20
Married (vs. not)
Men	−1.11	−1.55	−1.32	1.90c	0.05	−2.18*
Women	−0.24	−0.80	−0.53	−1.55	−1.78c	−1.68
Jewish ethnicity (vs. not)
Men	1.12	0.93	1.78c	1.52	−0.23	0.68
Women	2.74**	1.99*	1.40	1.26	−0.85	−0.22
Annual income ≥ $75,000 (vs. not)
Men	1.19	1.60	1.55	−1.15	1.81c	1.14
Women	1.05	0.26	−0.45	0.58	−1.01	−0.06
Employed full-time (vs. not)
Men	−1.21	1.39	0.62	−0.16	1.80c	−0.26
Women	−0.67	−0.98	−1.50	−0.79	−1.52	−1.47
Study site (GU vs. NY/NJ)
Men	0.96	0.46	0.31	0.37	1.47	1.67c
Women	2.21*	1.54	0.92	1.48	−0.21	0.27

^aWe included the baseline variable associated with the specified outcome within the general estimating equation models. For genetic testing distress, we used cancer-specific distress at baseline, as we did not have a baseline measure of genetic testing distress

^bFamily history total represents the total number of first and second degree relatives diagnosed with breast or ovarian cancer

^cP < 0.10

^*P < 0.05;

^**P < 0.01;

^***P < 0.001