Initial body weight | Final body weight | ||
---|---|---|---|
Group | Dose | (g) | (g) |
I (Normal control) | 5 mL/kg | 175.46±1.6 | 178.36±4.6 |
II (STZ) | 65 mg/kg | 172.52±2.6 | 148.21±2.3* |
III (STZ+MECI) | 250 mg/kg | 170.23±2.8 | 154.61±2.5† |
IV (STZ+MECI) | 500 mg/kg | 174.32±1.2 | 151.62±1.2† |
V (STZ+Gliben) | 0.5 mg/kg | 171.25±3.8 | 159.76±2.8† |
Values are expressed as mean ± standard error of the mean (n=6).
*P<0.001 compared with normal control.
†P<0.001 compared with STZ control group.
Gliben=glibenclamide; STZ=streptozotocin.