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. 2011 Aug 1;85(2):197–201. doi: 10.4269/ajtmh.2011.10-0070

Table 2.

50% inhibitory concentrations and 95% confidence intervals of antimalarial drug susceptibility patterns of Plasmodium vivax, China*

Drug Culture time < 24 hours Culture time ≥ 24 hours All cases
IC50, ng/mL 95% CI IC50, ng/mL 95% CI IC50, ng/mL 95% CI
Chloroquine 28.64 6.27–130.75 6.52 1.98–21.45 10.87 4.50–26.26
Mefloquine 4.15 1.05–16.38 4.25 1.31–13.79 4.21 1.88–9.42
Pyrimethamine 17.26 3.44–86.57 19.13 6.67–54.86 18.32 8.08–41.50
Quinine 20.63 7.53–56.58 7.89 3.14–19.79 11.82 6.20–22.56
Artesunate 0.20 0.12–0.33 0.10 0.05–0.18 0.13 0.09–0.20
Piperaquine 27.40 10.35–72.52 13.27 6.44–27.35 17.73 10.29–30.57
Primaquine ND ND 69.75 ND 69.75 ND
*

IC50 = 50% inhibitory concentration; CI = confidence interval; ND = not done.